H.E.L.P. stands for Heparin-mediated Extracorporeal LDL/Fibrinogen Precipitation.
H.E.L.P. is a treatment for patients with advanced coronary artey disease and hypercholesterolemia.
This extracorporeal apheresis procedure drastically lowers the blood concentration of major atherogenic risk factors LDL, fibrinogen, and lipoprotein(a) (Lp(a)).Current management of coronary artery disease consists of medical therapy designed to increase oxygen supply to the heart or to reduce myocardial oxygen consumption. Vasoactive agents, coronary angioblasty, and coronary bypass surgery have become routine techniques to improve oxygen delivery. Correspondingly, it is essential to cope with the underlying atherosclerotic process. For the majority of patients drug therapy is sufficient to normalize plasma LDL levels, but some patients, especially high risk patients require additional treatment.
If H.E.L.P. treatment is combined with cholesterol-lowering drugs, one treatment every fortnight is sufficient for most patients to maintain desired target levels. One treatment lasts two hours, time and quantity treated can be regulated individually.
H.E.L.P. treatment is established in the Heart Surgical Department and has proven efficient and safe in the long-term prevention of acute coronary syndromes and graft vessel disease after cardiac transplantation.